Testimonials and Endorsements for Masquelier's Authentic French Pycnogenols and OPCs
U.S. Patent Awarded for Prevention & Treatment of Heart Disease & Strokes
U.S. Patent Number: 5,720,956
U.S. Patent Awarded for Treatment of ADD/ADHD: Cited For Treating Attention Deficit/Hyperactivity Disorder.
U.S. Patent Number: 5,719,178
1947 First Testimonial: Edema
"In 1947 the renowned French chemist Jack Masquelier, professor emeritus of medicine at the University of Bordeaux, isolated the first OPC, a colorless substance, from the red skin of the peanut. He tells how he gave it to the wife of the dean of his faculty, who had severe edema from pregnancy; her swollen legs got so tired she could barely walk. ''Well, the dean''s wife was cured in forty-eight hours,'' says Dr. Masquelier. ''So there had to be something special about my extract.'' In 1950 the peanut-skin OPC became the first vasculo-protective medicine, known as Resivit and sold in France. About a quarter of a century later another drug based on Dr. Masquelier''s grape seed OPC, called Endotelon, made its debut in France. By 1979 Masquelier had also christened his brainchild "pycnogenols," a generic word describing in Greek its multi-faceted chemistry... Dr. Masquelier has also detected OPC in virtually all plants, red wine, and the peanut kernel itself. The current concentrated commercial sources are grape seeds and the bark of the French maritime pine tree. Dr. Masquelier also says OPC primarily accounts for the antioxidant, artery-protecting activity of red wine and tea." (2)
"In another study by Professor Leng-Levy, University of Bordeaux, 31 persons were given 90 milligrams of Pycnogenol (Masquelier''s OPCs) daily for two months. Their capillary resistance improved markedly and ecchymosis disappeared. The study subjects reported that their edema had vanished and their legs felt invigorated." (3)
"Italian scientists from the University of Florence studied the effect of Pycnogenol (Masquelier''s OPCs) on venous congestion in the legs - leg edema. The study involved 40 subjects consisting of 13 men and 27 women between the ages of 34 and 74, having an average age of 60 years. The subjects were randomly divided into two groups. One group served as the control group and received a placebo supplement that appeared identical to the Pycnogenol supplement but contained an inactive substance. The other group received 300 milligrams of Pycnogenol daily for 60 days.
"All of those taking the Pycnogenol had relief from at least some of the symptoms. There was a decrease in the feeling of heaviness in lower limbs in 11 percent of those receiving Pycnogenol after 30 days, and in 33 percent after 60 days.
"The swelling disappeared in 26 percent of those taking the Pycnogenol after 30 days, and in 63 percent after 60 days (circumference measured above the ankle before and after test). Pain in the lower limbs was totally relieved in 38 percent of those taking Pycnogenol after 30 days, and in 67 percent after 60 days." (4)
"I''d like to share a case history of one of my patients who suffered with varicose veins for almost 30 years. Last summer when this patient was in my office, he read some literature on the benefits of pycnogenols on the blood vessels. He was particularly interested in research studies that demonstrated pycnogenols benefits on varicose veins. He told me that he developed varicose veins at a very early age. He said that by the time he was 21 years old, he was suffering with symptoms of painful and tired legs. In his late twenties he developed phlebitis and an infection in both legs. His veins, from his groin to his ankles, in both legs, were swollen and inflamed. After two weeks of suffering with fever, pain and infection, he ended up in the hospital for an operation to strip the veins. For years after, the veins were enlarged and raised, and needless to say, unappealing to the eye. He decided to try pycnogenols. I suggested that he should consider, since he had had this condition for so long, that he should not expect to see a change overnight. He understood, and for the next three months he faithfully took doses of pycnogenols. I recently saw this patient again, and to my surprise, and his delight, the brown spots, and the tortuously pronounced veins, all the way from his thighs to his ankles, were remarkably improved." (6)
"Dr. G. Feine-Haake, a specialist in internal medicine in Hamburg, Germany, studied the benefit of 90 milligrams of Pycnogenol daily on 110 persons having varicose veins. Seventy-seven percent showed a clear improvement. Additionally, among the 41 individuals who had nightly calf cramps, 93 percent had an improvement in symptoms." (4)
Defuses High Blood Pressure
"French researchers have found that grape seed OPC increased capillary resistance by 25 percent in patients with high blood pressure and/or diabetes, compared with those taking a placebo sugar pill. Exciting new research by Professor Peter Rohdewald, a leading pharmaceutical researcher at the University of Münster in Germany, shows that pine bark OPC reduces adrenaline stress reactions that trigger high blood pressure. In animals, brain damage from strokes was much less in those first given OPC." (2)
"Andy had tried conventional prostate drugs (such as Proscar) but found them ineffective; saw palmetto, an herbal extract often prescribed by holistic doctors as a Proscar alternative, had also not helped him. Dr. Fleisher put Andy on Pycnogenol ... Andy''s prostate had gone from hard to soft and was nearly normal again in size." (9)
"Mel had an extremely high PSA blood level. (Prostatic Specific Antigen, PSA, is a blood enzyme that typically elevates in the presence of prostate cancer.) He had received radiation therapy and had chemotherapy twice. he said the cancer had metastasized into his spine. He was in constant pain. He had taken Pycnogenol for one month and had another PSA test. He said it had dropped to almost normal. He also stopped getting up at night to empty his bladder. In three months of taking Pycnogenol, his spine pain was gone and the color in his face came back to normal." (10)
"Take the case of Peter, a very successful art dealer in his mid-forties, whose normal schedule included flying back and forth to Asia once a month. But suddenly, sitting for hours was beginning to wreak havoc on his back, which had been the source for of chronic pain for years. A former college football player, he had developed a mild degenerative disc problem that now seemed to be getting worse. Trying to compensate, Peter had taken up golf and tennis. Typically, he was pushing himself too hard -- thirty-six holes on a Sunday morning was not unusual. His wife, familiar with his routine, grew used to helping him out of bed the following Monday.
"On a trip to Japan he mentioned his back trouble to a colleague, who told him about a substance called Pycnogenol. The colleague''s wife had been using it for a year to treat here arthritis symptoms. Her joint pain had been so reduced that she was now able to return to her daily regimen, which included a two-mile walk, without a hitch.
"Peter had been a patient for about three years when he first questioned me about Pycnogenol. ''Frankly,'' he told me, wincing as he sat down, ''I''m ready to try anything.''
"When he mentioned Pycnogenol, I did a thorough search in the medical literature. I discovered that there had been studies on it in France, Germany, and Italy, where laboratory research had been performed to observe how Pycnogenol performed on cells in a test tube, along with animal experiments. So confident were the Europeans of their test results that they were using it in three different ways: as an antioxidant, and anti-inflammatory, and an allergy medication. I told Peter that it was worth trying, especially since the studies supported Pycnogenol''s success rate; also the anti-inflammatory medications he had taken in the past had upset his stomach...
"Less than a week later he called me. ''I woke up today without the usual aches and pains. It''s such a noticeable difference that I had to tell you right away. I feel like I''ve been given a reprieve. I''m off to Bangkok tomorrow.'' Peter''s reaction to Pycnogenol was clear. Working as an antioxidant, Pycnogenol attacked those damaging free-radical molecules that our bodies create every day as a by-product of oxygen use. But it didn''t stop there; Pycnogenol also inhibited the release of histamine, enzymes, and prostaglandins that lead to inflammation, thereby helping to relieve Peter''s symptoms.
"These days Peter is more active than ever. He thoroughly enjoys his sports, and extended flights are no longer a problem. The amazing effects of Pycnogenol have made his lifestyle pain-free." (7)
Chronic Fatigue Syndrome
"Dr. Anthony W. Martin, D.C., Ph.D., of Timmins, Ontario, says that Pycnogenol is of particular benefit to patients suffering from fibromyalgia and chronic fatigue syndrome (CFS). ''I started treating CFS in 1985, but it wasn''t until Pycnogenol that I was able to help these patients.'' he says.
"Dr. Martin says the he typically recommends that his CFS patients -- some of whom have included professional hockey and baseball players -- adopt a low-carbohydrate, high-protein diet, and supplement with a therapeutic dose of 200 mg to 400 mg of Pycnogenol daily. ''I can get a decrease in most CFS symptoms in three to six weeks,'' he says. ''Pycnogenol seems to give these people a jump start.''" (8)
"''It Stopped My Eye Disease.'' Madison Dixon, age seventy-six, an optometrist in a small town in southern Georgia, had been using antioxidants, mainly vitamin C and beta-carotene, to retard two serious age-related eye problems - cataracts and macular degeneration - for nearly forty years. So when he heard about a new super-potent antioxidant from France called Pycnogenol, he was excited, thinking it might work even better to save sight. In particular he was worried about the diminishing vision in his own right eye, due to macular degeneration, in which the macula, the tiny center of the retina, disintegrates, sometimes eventually causing blindness. There is no medical or surgical cure for the condition, although studies have shown that antioxidants can slow its progression.
Dr. Dixon started taking Pycnogenol in 1993. He was elated. His macular degeneration did not continue to worsen, nor did his cataracts. ''My vision uncorrected is still 20/30,'' he says.
"''I credit the slowdown of disease to first Pycnogenol and then grape seed extract.'' Initially he took eight capsules of Pycnogenol a day... Then he switched to less expensive grape seed extract OPC, which he finds just as effective for his eyes and even more therapeutic for his osteoarthritis. A big plus: The grape seed extract (OPC) ''costs about half as much.'' Until his recent retirement he also recommended OPC grape seed extract and Pycnogenol to his patients, whose eyes, he says, invariably improved. ''I do not know a single patient who did not benefit,'' he says.
"The grape seed (OPC) antioxidant performed another miracle for his wife, Jane, how has advanced rheumatoid arthritis, he says. She has had two knee replacements and one hip replacement, and was facing replacement of the other hip. ''The doctor looked at an X-ray of the other hip and said, "In about six months to a year we''ll be doing that one,"'' recalls Dixon. ''That was about four years ago. The doctor is surprised, but we''re not even thinking about surgery now. To tell the truth, since taking the grape seed extract (OPC), that hip gives her fewer problems than the one that was operated on.''" (2)
Research Findings for Diabetics
"Numerous reports support the use of OPCs for problems that arise with diabetes. Some of these findings include:
"French doctors found that diabetics who took an OPC supplement daily significantly decreased the risk of damage to their vision. Rupturing of the tiny capillaries in the retina was reduced by as much as 90 percent.
"One diabetic patient with extremely poor circulation complained of numbness, pain, and coldness in a lower limb. When given OPC supplements on a regular basis, these symptoms dramatically improved. Doctors noted that blood flow in the main artery to the foot increased - so much so that the skin temperature of this previously cold limb actually rose.
"Excessive excretion of albumin, a protein, predicts kidney damage in diabetics. Bringing down this rate has been shown to be an effective strategy for postponing this damage. Numerous studies have shown that OPC supplements keep the body from excreting excessive amounts of this important substance." (5)
"It Cured My Allergies. European studies have also shown that OPC extracts suppress release of histamine. The implications are evident for those suffering from respiratory allergic reactions, notably hay fever. OPC can act just as an antihistamine. Indeed Marian Holtan-Jansen, director of new products at a major U.S. supplement company, was quite astonished to find that OPC stopped her pollen allergies for thirteen years after only three days. She had heard that OPC relieved allergies, but she didn''t believe it.
"''I discounted it. I am a natural skeptic,'' she says. But when she was reviewing the scientific evidence for the French OPC drug Endotelon, now called Dr. Jack Masquelier''s True OPCs in this country, she say research on its effectiveness as an antihistamine. She said, ''Well, okay, I''ll try it. She had taken many antiallergy drugs but hated them. ''I took all kinds of prescriptions, such as Seldane, and everything I took left me feeling kind of dopey and semifunctional.'' She took the French-recommended 300 milligrams a day of Dr. Masquelier''s OPC as an antihistamine.
"''Within three days, what had been a terrific case of blocked sinuses, runny eyes, and scratchy throat was gone. I was just amazed.'' She continues to take 150 milligrams of the OPC every day and has ''never had another flare-up - even in the worst allergy season.''" (2)
Attention Deficit and Hyperactivity Disorder
"A preliminary study by Marion Sigurdson, Ph.D., a psychologist in Tulsa, Oklahoma, who specializes in treating attention deficit disorder, has found striking benefits from OPC. Using a blend of pine bark and grape seed (Dr. Masquelier''s OPC product), Dr. Sigurdson found that it worked just as well as the commonly prescribed stimulant medications, including Ritalin, on thirty children and adults diagnosed with ADD. The subjects were given a battery of computerized and behavior tests to judge their attention, concentration, and other important factors in ADD under various circumstances: when they were either on or off their usual stimulant medications, or on the OPC alone. When they were off their medications, their ADD deteriorated. On their medications, they were much improved. But when they took daily doses of the OPC grape seed-pine bark mixture, their scores and behavior were just as improved as when they took stimulant drugs. In other words, the OPC equaled the drugs in most subjects... (Many of the subjects also had other positive effects: decreased heart beat, disappearance of tennis elbow, relief of acne, improved sleep and mood.)...
"STEVEN''S MIRACLE ''I Can Now Finish What I Start.'' Looking back, clinical psychologist Steven Tenenbaum realizes he has always had problems concentrating, paying attention, and focusing. He did poorly in school, especially in math... He was hyperactive-impulsive and had problems with attention. But not until 1984, at age twenty-five when he was getting his doctorate at St. Louis''s Washington University to become a psychologist, did he understand he had a neurological condition called attention deficit hyperactive disorder or ADHD, characterized by a short attention span, impulsivity, and sometimes hyperactivity. The condition is said to affect 4 to 7 percent of the population, both youngsters and adults.
"Under ordinary circumstances, Dr. Tenenbaum would have relied on stimulant drugs, such as Ritalin, Dexedrine, or Cylert, widely prescribed for ADHD. But he had learned to fly recreationally, and if he took such drugs he could not keep his pilot''s license under Federal Aviation Administration (FAA) regulations. So he toughed it out for many years without medication. After getting his doctorate, he set up the Attention Deficit Center in St. Louis, which specializes in counseling and developing coping abilities in children with ADHD.
"In 1995 he began to hear about alternative treatments for ADHD from patients, parents, and people on the Internet. The buzz on one such substance, Pycnogenol (Masquelier''s OPCs invention), was particularly fascinating to Tenenbaum. He tried it and was thrilled. ''My effectiveness has increased by about 40 or 50 percent in the year and a half I''ve been on it. I can now finish what I start.'' he raves. Without his three-times-daily regimen of the pine bark extract, he becomes mentally scattered and unable to focus... "it produces the increase in attention, the increase in focus, the decrease in emotional reactivity.'' He also feels it elevated his mood. Tenenbaum notes that like prescription stimulants, the OPC seems to work for some but not others. It does not eliminate the problem, of course, but only helps control it. ''It just dampens some of the intensity of the disorder,'' he asserts."
"A broad-spectrum nutrient with numerous applications, Pycnogenol is unlike any other antioxidant. I choose it frequently to counteract free radicals and enhance the active lives of the men and women who are using my Vitality Medicine program. I''ve seen Pycnogenol work for my patients time and time again, in a number of different ways:
"On skin: When added to the regimen of David, thirty-two, it meant a significant decrease in the severity of his psoriasis, a skin condition marked by scaling and red patches. His itching diminished, and wearing short sleeved shirts to play racquetball was no longer embarrassing.
"On blood vessels: For Kellie, thirty-seven, it meant a reduction of edema, the swelling in her lower legs due to water retention, a condition that began when she became pregnant, and was still noticeable when her daughter was a year old. For the first time in almost two years, her legs were back to their normal shape.
"On the gastrointestinal system: For James, forty-three, whose spastic colon flared when his company was downsized and he had to take on more work, it meant fewer distractions due to discomfort.
"On collagen and elastin: For Amy, twenty-eight, who loved the sun, it offered protection against damaging rays and, therefore, premature aging.
"On inflammation: For Ted, forty-nine, an avid marathon runner, it meant quicker healing from sports-related injuries.
"On allergies: For Nick, thirty, it meant relief from hay fever that plagued him yearly." (7)
How can I identify the
Masquelier''s Authentic FRENCH PYCNOGENOL®* and OPCs in the American market?
Masquelier named and trademarked his invention PYCNOGENOL® in France, but now he cannot use his trade name within the United States because of his former International broker, Horphag. According to Dr. Masquelier (who does not speak English): "Horphag plans coup and secretively files for registration of the trademark in it''s own name... This covert attempt to grab control by means of plain theft of intellectual property set the stage for the current trademark problems." (e) Therefore, only Horphag, who now sells a pine bark based extract - not manufactured or endorsed by Masquelier - may legally use the trademark, PYCNOGENOL, in the U.S. This is why there is much confusion in the American marketplace.
MASQUELIER''s® original and only industrial extraction factory, located in France. "OPC ''tea'' made at Berkem''s, the OPC factory in Gardonne (France). Berkem extracts vegetal materials such as pine bark and grape seeds according to Masquelier''s original extraction method. The factory has been working with Masquelier since the earliest days of OPC production on an industrial scale." (f)
Horphag''s extract does NOT carry the trademark PYCNOGENOL in France, and Masquelier''s extract does not carry the trademark PYCNOGENOL in America. Therefore, while the legal issues of terminology are settled in the United States courts, look for MASQUELIER''s® name and patent on the bottle. These products GUARANTEE Masquelier''s genuine FRENCH PYCNOGENOL extract to distinguish his original OPCs products from inactive bioflavonoids, generic grape seed and pine bark extracts and other offshoot products, passed off by unauthorized competitors.
The Safety Factor
Masquelier''s authentic FRENCH "Pycnogenol studies carried out at the Pasteur Institute in Lyon, France, have shown it to be nontoxic to humans. In one study, daily doses of up to 35,000 mg were given for six months, with no adverse effects. Pycnogenol should be viewed as a completely safe nutrient." (a) Analytical batch testing serves consumers in an important but indirect way. It is the supplier''s guarantee to purchasers and authorities that the consumer gets the product that was tested in research. MASQUELIER''s Authentic FRENCH OPCs routine and extensive analytical batch-to-batch consistency testing both in France and in the USA serves as a guarantee of constancy and uniqueness for this classic, authentic, researched and renowned product. (d)Most especially gratifying is that so many are finding this patented compound is literally providing a non-drug, new lease on life for many thousands of people.
The Proprietary Formula is not available in any store.
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**PYCNOGENOL is a registered trademark of the International Nutrition Company (France, Portugal, Australia, South Korea, and other countries) and Horphag Overseas Ltd. (U.S. and other countries) protected by U.S. Patent # 4,698,360 and international patents. Professor Jack Masquelier is the inventor of both the patent and the term, "PYCNOGENOL". And now Prof. Masquelier''s French companies, including Société Civile d''Investigations Pharmacologiques d''Aquitaine (SCIPA), are members of the International Nutrition Company (INC) group of companies.
Masquelier named and trademarked his invention PYCNOGENOL® in France, but now he cannot use his trade name within the U.S. because of his former International broker, Horphag. According to Dr. Masquelier (who does not speak English): "Horphag plans coup and secretively files for registration of the trademark in it''s own name... This covert attempt to grab control by means of plain theft of intellectual property set the stage for the current trademark problems." Therefore, Horphag changed extraction manufacturing companies and now sells a DIFFERENT pine bark based extract - NOT manufactured or endorsed by Masquelier. Horphag''s extract does NOT carry the trademark PYCNOGENOL in France. On the other hand, Masquelier''s extract does NOT carry the trademark PYCNOGENOL in Amercia. This is why there is much confusion in the American marketplace. Therefore, while the legal issues of terminology are settled in the United States courts, look for MASQUELIER''s® name and patent on the bottle. These products GUARANTEE Masquelier''s genuine FRENCH PYCNOGENOL extract to distinguish his original OPCs products from inactive bioflavonoids, generic grape seed and pine bark extracts and other offshoot products, passed off by unauthorized competitors. Prof. Masquelier''s authentic oligomeric proanthocyanidins (OPCs) from Maritime Pine tree bark and grape seeds are the result of 50 years of scientific research and development. The original MASQUELIER''s products are unsurpassed, well defined, safe and highly efficaceous patented products. Look for the authentic MASQUELIER''s®. You can feel the difference!
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NOTE: Much of the information here presented has been addressed by literally hundreds of individuals seeking the same solutions, to the same answers, with which you are now engrossed. The research contained on this site is general in nature and has been compiled, reviewed and corrected to the best of the authors ability. It is presented for educational purposes. It is your personal responsibility to determine the validity of any and all information presented. Each nutritional supplement product is NOT a drug and NOT represented as having any medicinal value. This is not intended to diagnose, treat, cure or prevent any disease. The author hereby declares that this writing is made without any statement or declaration which would represent that he/she is a doctor*, licensed medical professional, or other type of medical counselor. None of the statements on this site are an endorsement of any particular product, or a recommendation as to how to treat any particular disease or health-related condition. *IF THERE ARE ANY QUESTIONS THAT COME TO MIND THAT MAY NOT BE EASILY ANSWERED THROUGH YOUR RESEARCH AND THE HERE INCLUDED CITATIONS, PLEASE CONSULT THE APPROPRIATE MEDICAL PROFESSIONAL. The information presented here is done so under the benefit and authority of the First Amendment to the Constitution of the United States of America, ordained and preserved for the benefit of all.
1. James F. Balch, M.D., "The Super Antioxidants - Why They Will Change The Face of Healthcare in the 21st Century" M. Evans and Company, Inc. (1998).
2. Jean Carper, "Miracle Cures : Dramatic New Scientific Discoveries Revealing the Healing Powers of Herbs, Vitamins, and Other Natural Remedies"; HarperCollins Publishers (1998).
3. Prof. Arcangeli, University of Florence (June 16, 1989) as reported by: Richard A. Passwater, Ph.D., "The New Superantioxidant Plus," Keats Publishing (1992).
4. Richard A. Passwater, Ph.D., "The New Superantioxidant Plus," Keats Publishing (1992).
5. Corrinne T. Netzer''s "Big Book of Miracle Cures: Amazing Scientific Breakthroughs in Vitamins, Herbs, and other Alternative Remedies Tested and Proven to Prevent and Treat Dozens of Illnesses," Dell Publishing division of Random House, Inc. (1999).
6. James D. Krystosik, D.C., "PYCNOGENOL Pine Bark / Grape Seed: Nature''s Prescription for Aging, Allergies..." Good News Press.
7. Steven Lamm, M.D. and Gerald Secor Couzens, "Younger at Last: The New World of Vitality Medicine," Simon & Schuster.
8. Anthony W. Martin, D.C., Ph.D. "Researchers Present Latest Findings On Pycnogenol" - excerpts from the Fourth International Symposium on Pycnogenol in Biarritz, France. Nutrition Science News, July 1997; a publication of Natural Foods Merchadiser and New Hope Communications, Boulder Colorado, USA.
9. Patient records of Mitchell A. Fleisher, M.D., The Blue Ridge Medical Center, Arrington, Virginia, USA.") "The Holistic Physician" Issue No. 11, ALTERNATIVE MEDICINE DIGEST, Future Medicine Publishing, Inc.
10. Patient records of Dr. W. LaMar Rosquist, N.D., D.C. Salt Lake City, Utah. "LIFE-CHANGING CASE HISTORIES"
11. THE INTERNATIONAL NUTRITION COMPANY SPECIAL REPORT, "MASQUELIER''s Original OPCs and 10 grape seed extracts AN INDEPENDENT, REPRODUCIBLE STATE-OF-THE-ART COMPARATIVE ANALYSIS," November 1997.
a. Steven Lamm, M.D. and Gerald Secor Couzens, "Younger at Last: The New World of Vitality Medicine," Simon & Schuster.
b. Jean Carper, "Miracle Cures : Dramatic New Scientific Discoveries Revealing the Healing Powers of Herbs, Vitamins, and Other Natural Remedies"; HarperCollins Publishers (1998).
c. Morton Walker, D.P.M., "Comparison Between OPCs, the World''s Most Powerful Antioxidants, and Grape Seed Extracts," MEDICAL JOURNALIST REPORT OF INNOVATIVE BIOLOGICS.
d. THE INTERNATIONAL NUTRITION COMPANY SPECIAL REPORT, "MASQUELIER''s Original OPCs and 10 grape seed extracts AN INDEPENDENT, REPRODUCIBLE STATE-OF-THE-ART COMPARATIVE ANALYSIS," November 1997.
e. Bert Schwitters and Prof. Jack Masquelier, "PYCNOGENOL in the U.S.A." for Prof. Jack Masquelier (France), S.C.E.R.P.A. (France), C.E.P. (France), Holland Health (The Netherlands), October 1991.
f. Bert Schwitters and Prof. Jack Masquelier, "OPC In Practice: The Hidden Story of Proanthocyanidins, Nature''s Most Powerful and Patented Antioxidant," Alfa Omega Editrice, Publishers.